How much can you make with clinical trials?

How much can you make with clinical trials?
Discover the earning potential of participating in clinical trials. This blog post breaks down how much you could potentially make, factors influencing your payout, and important considerations before signing up for a trial.

Share This Post

Table of Contents

Understanding Clinical Trials

Clinical trials play an integral role in the advancement of medical research. They provide valuable insights that help to identify new treatments, document side effects, compare existing and promising therapies, and conduct in-depth study on how a treatment affects various demographics such as age, gender, ethnicity, and stages of a disease. Conducted in a controlled environment, these trials are designed to systematically gather data and derive conclusions regarding the efficacy and safety of a medical procedure or a drug before it comes to the market.

Participation in a clinical trial comes with its own set of protocols and processes. Each trial is divided into different phases, ranging from Phase I, where the safety of a new treatment is tested on a small group of people, to Phase IV, where after-market surveillance occurs after the treatment has been approved for use. The data collected from these trials is then extensively analyzed to determine the next steps in medical advancement. Parallel to this, regulatory bodies such as the FDA in the U.S. or the EMA in Europe scrutinize this information, ensuring the study fulfills all ethical and safety stipulations.

The Process of Participating in Clinical Trials

To become part of a clinical trial, the first step is often pre-screening. This is a process where the participant’s medical history, current health status, and suitability for the trial are assessed. Pre-screening can be done remotely via phone or online, or in-person at a clinical research facility. It’s important to be honest and comprehensive during this phase as the information collected is crucial for ensuring participant safety and the integrity of the study data.

Once selected for a trial following the pre-screening phase, participants enter the informed consent process. This involves a detailed discussion of the trial, its objectives, procedures, potential benefits, and risks. The participant has the chance to ask questions and discuss any concerns they may have with the research team. It’s only when the participant fully understands these aspects and gives written consent, they are enrolled in the trial. Participating in clinical trials typically involves regular visits to the clinical research facility for examinations, tests, and administration of the investigational product or treatment. Each visit, its purpose, and the procedures to be carried out are clearly outlined in the trial protocol, which is shared with the participant during the informed consent process.


After enrollment, participants are closely monitored throughout the trial. This includes regular health check-ups, laboratory tests, and follow-up visits to assess the safety and effectiveness of the investigational product or treatment. It’s crucial for participants to adhere strictly to the instructions given by the research team during this phase.

• Pre-screening:
◦ Assessment of participant’s medical history
◦ Evaluation of current health status
◦ Determination of suitability for trial

• Informed Consent Process:
◦ Detailed discussion about trial objectives and procedures
◦ Explanation of potential benefits and risks
◦ Opportunity for participant to ask questions and discuss concerns
◦ Written consent from participant after full understanding

• Trial Participation:
◦ Regular visits to clinical research facility
◦ Examinations, tests, administration of investigational product/treatment as per protocol
◦ Protocol shared with participant during informed consent process

Post-enrollment monitoring is also a critical part of participating in clinical trials:

• Monitoring During Trial:
• Regular health check-ups
• Laboratory tests
• Follow-up visits

The end goal is not only ensuring that new treatments are safe and effective but also improving overall patient care. Participating in a clinical trial can be an empowering experience that contributes significantly towards advancing medical science.

Types of Clinical Trials and Their Compensation

Clinical trials are primarily divided into four categories: observational studies, interventional studies, expanded access studies, and diagnostic studies. Observational studies involve researchers observing subjects in their natural settings without inducing changes, while interventional studies involve the investigator directly manipulating and studying variables. Expanded access studies provide treatment options for participants with severe diseases who might not meet the criteria for other research studies. Diagnostic studies are conducted to find better ways to detect certain disorders or conditions.

These four types of clinical trials have varying compensation scales. Generally, interventional studies tend to pay more because they involve more risk and direct engagement from the participants. Observational studies, meanwhile, generally pay less as these studies are primarily observational. Payments for expanded access trials vary significantly as it largely depends on the disease type and the potential value of the treatment. Diagnostic trials’ compensation is typically a little less than interventional studies, as they mostly involve testing already-existing or newly-developed diagnostic processes.

Factors Influencing Clinical Trial Pay Rates

The compensation received by participants in a clinical trial can be influenced by several factors. A primary factor to consider is the complexity and invasiveness of the procedures involved. For instance, trials that require participants to undergo invasive medical procedures or often have more extended stays in the medical facility tend to offer higher compensation. This is to account for the increased time commitment and potential discomfort or risk to the participant.

Another significant influencing factor is the duration of the trial. Longer clinical trials usually require a higher level of commitment from the participant and therefore typically offer higher compensation. In addition, trials that require specialized populations, such as those with particular medical conditions, or genetically unique individuals, may also offer higher pay rates due to the difficulty in finding suitable candidates. These are just a few examples of how the specifics of a clinical trial can affect the pay rates for participants.

Benefits of Participating in Clinical Trials

Participation in clinical trials can yield numerous advantages beyond monetary compensation. The most apparent benefit lies in the direct access to innovative treatments not yet available to the public. As medicine and healthcare are ever-evolving fields, joining clinical trials allows participants to be at the forefront of these advancements. This can be particularly beneficial for individuals with conditions that have been unresponsive to existing treatments, or for which no established cure exists.

Additionally, clinical trial participation plays an essential role in progressing medical knowledge and developing new treatments. By contributing to these trials, participants indirectly support the wellbeing of future patients and the wider medical community. Their participation aids in turning medical hypotheses into concrete treatments that could potentially save lives. At the same time, it also offers valuable insight into the complex interplay of genetics, lifestyle factors and environmental influences on health outcomes.

Potential Risks of Clinical Trials

Participation in clinical trials is not without its share of risks and drawbacks. Some of these have direct physical consequences for the participant. Depending on the nature of the trial and the drugs or procedures being tested, side effects can range from mild discomfort to severe reactions. Moreover, there is always the inherent risk of unknown complications arising due to the experimental nature of the treatments. Some participants might even experience worsening of their condition or develop secondary conditions as a result of the trial.

Apart from the physical risks, there are the psychological implications to consider as well. The uncertain outcomes can cause significant anxiety for participants, who might also face social and ethical dilemmas regarding the use of experimental treatments. Moreover, depending on the duration and requirements of the trial, participants may be required to invest significant amounts of time, which could disrupt regular life routines and work schedules. This may inadvertently lead to financial implications, creating another layer of potential strain and inconvenience.

Institutional Review Boards in Setting Compensation

Institutional Review Boards (IRBs) play a critical part in determining compensation rates for clinical trial participants. They are mandated with safeguarding the rights and welfare of individuals participating in research studies. A key function of this involvement includes evaluating and approving the payment proposed for participants. This stipend is carefully assessed to ensure it is regarded as a fair reimbursement for time, travel, and inconvenience, but not as a means to unduly influence potential participants.

IRBs are governed by federal regulations to ensure compliance and to maintain an ethical balance. In addition to reviewing and approving proposed participant compensations, they also closely monitor the trial to ensure that payments are made as per the approved schedule. These boards also hold the power to suggest changes to the payment plan, either increasing or decreasing it based on the demand of the study and the responsibilities of the participants. Notably, compensation is not meant to entice potential patients into participating, but rather to appropriately acknowledge their contribution to scientific advancement.

Ethical Considerations in Clinical Trial Compensation

Ethical considerations play an essential role in determining compensation for clinical trial participation. In essence, they set boundaries that ensure neither parties involved is exploited and that every procedure is conducted in the best interest of participants. Various ethical guidelines serve as a roadmap to establish fair compensation, such as the Declaration of Helsinki and the Belmont Report, which focus on protecting the rights, safety, and well-being of the human subjects participating in the research.

However, there’s a thin line between stipends and incentives, and determining an appropriate compensation rate can be a complex process vulnerable to ethical dilemmas. If the compensation is significantly high, it could coerce financially vulnerable people into taking risks they might otherwise avoid. Conversely, low or no compensation could prevent potential participants from joining a trial due to the cost associated, such as time, transportation, or accommodation. Hence, the task lying ahead for the researchers is to strike a balance, ensuring the benefits of participation outweigh the risks, without crossing into the realm of undue influence or coercion.

Case Studies: Earnings from Different Clinical Trials

Clinical trial participants come from various walks of life and their reasons for engaging vary as well. While researching Reddit we found 2 cases that we wanted to share with you.

The case of John, a 38-year-old engineer, is particularly enlightening. He participated in a phase III clinical trial studying the effects of an innovative drug on migraines. For his time and efforts, which spanned over two visits in a three-month period, John received $700. This amount effectively compensated his travel expenses and took care of two months of his gym membership fee.

In contrast, Emily, a 22-year-old college student, participated in an observational clinical trial that required her weekly check-ins and general health assessments for six months. The trial didn’t involve testing any new medications, therefore, the risk factor was considerably less compared to interventional trials. Emily received a compensation of $1000 over the course of the trial, which greatly supported her with her college-related expenses. These case studies indicate the range of compensation, largely dependent on the type, duration, and demands of a specific clinical trial.

Maximizing Earnings from Clinical Trial Participation

To optimize financial gains from involvement in clinical trials, a well-thought-out strategy is necessary. One crucial step is conducting exhaustive research to pinpoint trials that offer the most compensation. It would be beneficial to focus on trials that are in the late-stage of research or those funded by large pharmaceutical companies, as these typically have bigger budgets for participant compensation. Attending numerous trials, provided they do not overlap and imply health risks, could also bolster one’s overall earnings.

Additionally, understanding the terms of the compensation package is critical. Certain trials offer a lump-sum payment, while others disburse funds incrementally throughout the trial. It’s important to ensure that the payment terms align with your financial needs. Furthermore, volunteering for trials involving overnight or extended stays usually comes with added compensation. Ultimately, while the opportunity to earn can be considerable, it should be balanced against the potential risks and the time commitment involved.

Subscribe To Our Newsletter

Get updates and learn from the best

More To Explore

Get the latest Surveys in your Inbox For Extra Cash

No Spam – Only Valuable Reviews.